TB Symptoms - Causes, Treatment, Medicine

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Understand Tuberculosis Symptoms for Timely Treatment

 

Finding out the symptoms of TB(Tuberculosis) earlier is significant as it helps in the faster treatment and prevents any further complications. The initial symptoms of TB are commonly include a continuous cough for three weeks or longer, along with the other symptoms. The symptoms of TB in babies include Fever, failure to thrive, lethargy, irritability, and in a few cases, breathing difficulty or pneumonia-like symptoms.  


To identify TB symptoms, a medical professional can go through TB blood or skin tests, chest X-rays, and lab tests for TB bacteria. Finding out the TB symptoms at home is not possible. However, TB symptoms like a persistent cough, coughing up blood or mucus, Fever, night sweats, Fatigue, chest pain, or weight loss warn you about future conditions. 


Tuberculosis(TB) is seen in countries such as India, China, Indonesia, the Philippines, Pakistan, Nigeria, Bangladesh, and the Democratic Republic of the Congo. TB has caused an estimated 1.2 million deaths yearly. Thus, it is better to find out the symptoms of Tuberculosis to provide proper treatment.  

 

TB Symptoms 


There are many TB symptoms that help determine if a person is affected by TB. 


What are the Symptoms of TB?  


The following are the common symptoms of TB disease. 

  • A cough lasting three weeks or longer
  • Chest pain
  • Coughing up blood or sputum
  • Fatigue
  • Weight loss
  • Loss of appetite
  • Chills
  • Fever 
  • Night sweats

 

Signs of TB


Brain TB symptoms include Headache, Fever and chills, Nausea and vomiting, sensitivity to light, stiff neck, mental status changes, seizures, sleepiness, aches and pains, Loss of appetite and Tiredness. Let's discuss neck TB symptoms here. Neck early-stage neck TB symptoms include painless, slow-growing swelling in the neck, along with general symptoms such as Fever, sweats at night, and weight loss. Skin TB occurs with different skin lesions, such as inflammatory papules, ulcers, pustules, nodules, and verrucous plaques, along with systemic symptoms such as weight loss, Fever, and night sweats. There are several bone TB symptoms. Bone tuberculosis (TB) symptoms include stiffness, continuous pain, swelling, and limited movement in the affected part, along with systemic symptoms like Fever, weight loss, and Fatigue.   

 

What is TB(Tuberculosis)?


Tuberculosis (TB) refers to a serious infectious disease that happens as a result of the bacterium Mycobacterium tuberculosis; basically affects the lungs, but it also affects other body parts as well.

 

Types of TB


There are different types of TB. Here are the different Tuberculosis(TB) types.

 

  1.  Pulmonary TB : A common type of TB is pulmonary (lung) tuberculosis. This most common form of TB, is when the bacteria basically infect the lungs. 
  2. Extrapulmonary TB : Extrapulmonary TB is a type of TB that affects organs other than the lungs, like the lymph nodes, joints, bones, kidneys, brain, or other regions. 
  3. Latent TB : Latent TB is a TB state in which the TB bacteria is present in the body, but it is inactive and does not cause any symptoms or illness. Characteristics: This type is not contagious, and they cannot spread the Disease.
  4. Active TB : In Active TB, the bacteria actively multiplies and causes symptoms and illness.
  5. Drug-resistant TB : Drug-Resistant TB is usually resistant to more than one standard TB medications. This Drug-Resistant TB is classified into two types, as Multidrug-resistant TB (MDR-TB) and Extensively drug-resistant TB (XDR-TB).

 

Causes of TB


The main cause of Tuberculosis(TB) is bacteria (Mycobacterium tuberculosis), which mostly affects the lungs. TB gets spread through the air if the people with lung TB do activities like coughing, sneezing or spitting. A person becomes infected by inhaling some germs. Each year, 10 million people are affected by Tuberculosis (TB).   

 

Risk Factors of TB 


We have discussed the causes and symptoms of TB, so let's see the risk factors. There are some risk factors for TB, they include : 

 

  • Having close contact with someone who has active TB. 
  • Working in regions with high TB rates
  • Living in countries with high TB rates
  • People with HIV/AIDS have a great risk of developing active TB disease. 
  • As Diabetes weakens the immune system, it increases the TB risk. 
  • Severe could weaken the immune system. 
  • Certain cancers of the head, neck, blood, etc., and their treatments could weaken the immune system.  
  • Malnutrition or low body weight, cancer treatments like chemotherapy, medications to prevent rejection of transplanted organs and long-term use of prescription steroids could weaken the immune system. Thus, they stay as a risk factor for TB. 
  • Substance use, such as injection drug use and Silicosis, are also the risk factors of TB. 
  • Smoking, using other tobacco products, Alcohol use, Undernutrition, living in crowded areas, and poverty are the other risk factors of TB.

 

Treatment for TB


Tuberculosis (TB) treatment basically involves a 6-month course of antibiotics, it often includes isoniazid and rifampicin, with the extra drugs such as pyrazinamide and ethambutol for the first 2 months. 

 

  • Active TB disease treatment involves standard treatment, such as providing a 6-month course of four antibiotics. 
  • Drug-resistant TB uses the Directly Observed Therapy (DOT) option. 
  • Latent TB Infection Treatment involves Preventive Treatment(antibiotics for 3 to 6 months) and Shortened Treatment Options(treatment to only 1 or 3 months). 
  • If TB spreads to the parts like the brain, spinal cord, or the region around the heart, then you might be required to intake steroid medicines for some weeks.

 

The methods to manage the symptoms of TB include : 


Foods to Eat in TB


Eating some foods helps with fast recovery from TB. Here are the foods to be included during TB.  

 

CategoryItems
Lean meatsChicken, turkey, and lean beef.
Fish and seafood Salmon, tuna, and shrimp.
Eggs and dairy productsMilk, yogurt, and cheese.
Legumes and beansChickpeas, Lentils, and kidney beans.
Nuts and seedsWalnuts, Almonds,  and chia seeds.
Other Protein rich foods Soy, tofu or Paneer.
Fruits rich in Vitamin COranges, papayas, and guavas.
VegetablesLeafy greens (like spinach, kale), sweet potatoes and  carrots.
Iron-rich foodsPoultry, fish, Lean red meat, fortified cereals, beans, lentils, and dark leafy vegetables. 
Foods rich in B complex vitaminsGrains, Seeds, nuts, fish, chicken, and cereals. 
Foods rich in Zinc Nuts and seeds like sunflower seeds, pumpkin seeds, chia seeds, and flaxseeds.

  

Foods to Avoid during TB


There are some foods which have to be avoided to prevent further complications. Here are those foods that have to be avoided during TB. 

 

CategoryItems
Sugary drinksEnergy drinks, Sodas, and sweetened juices.
Refined grainsPasta, White bread, and rice. 
High-sugar snacksCookies, cakes, and candies.
Processed foodsCanned foods, packaged snacks, and sugary cereals.
Fried snacksFries, Chips,and fast food.
Trans fat-rich foodsMargarine and processed junk food. 
High-fat meatsSausage, Red meat, and bacon. 
AlcoholAlcohol can disturb TB medications and worsen liver damage.
Caffeine High amounts of caffeine could result in the dehydration and disrupt sleep patterns.
Spicy FoodsSpicy foods cause irritation to the digestive tract and worsen symptoms. 
Raw or Undercooked FoodsRaw or undercooked meats, eggs, and unpasteurized dairy products may cause  the risk of foodborne illnesses.

 

TB Medications


Some medications help in TB treatment; let's see them. 

 

Medicine NamesFormulaUsed As
Isoniazid (INH)C6H7N3OFirst-line medications 
Rifampin (RIF) C43H58N4O12First-line medications
Pyrazinamide (PZA)C5H5N3OFirst-line medications 
Ethambutol (EMB)C₁₀H₂₄N₂O₂First-line medications 
StreptomycinC₂₁H₃₉N₇O₁₂First-line medications 
FluoroquinolonesC9H6FNOSecond-line medications 
CapreomycinC25H44N14O8Second-line medications 
BedaquilineC32H31BrN2O2Second-line medications 
Delamanid C25H25F3N4O6Second-line medications
EthionamideC8H10N2SSecond-line medications
Para-aminosalicylic acidC7H7NO3Second-line medications 
CycloserineC3H6N2O2Second-line medications


These medications will only be provided by your Doctor, you must not take these tablets for TB, without his/her prescriptions.  

 

Recovery Time for TB


Recovery from Tuberculosis (TB) involves taking a 6-month course of antibiotics, though the duration of treatment can vary based on the type of TB, the severity of the TB, and whether drug resistance is present. Babies with active TB typically begin feeling better within a few weeks of starting treatment. But it's important for them to complete the full course of antibiotics, which can last 6 months or longer, to ensure the infection is eradicated and prevent recurrence or drug resistance.

  

How to Prevent TB?


In general, one can prevent TB by following the below lifestyle changes. 


1. Get Medical Attention


If a person experiences symptoms such as prolonged cough (for 3 weeks or above), Fever, unexplained weight loss, or night sweats, then get medical attention promptly.


2. Undergo Medical Tests


If you are at increased risk (e.g., close contact with people with TB, HIV positive), then undergo the TB diagnostic tests. 


3. Finish Treatment


If you get diagnosed with TB, then take the full course of prescribed medications to prevent the spread of the TB disease. 


4. Follow Good Hygiene


Always cover your mouth and nose while you cough or sneeze, ideally with a tissue paper, and dispose that tissue paper properly.  
Next, wash your hands frequently, particularly after coughing or sneezing. 

Have proper ventilation in your home and workplace. 

 

5. Avoid close contact With TB Patients


Avoid close contact with others active TB, if you have active TB, particularly with those at higher risk. 


6. Respiratory Hygiene 


Have respiratory hygiene practices, like offering masks and tissue papers and proper ventilation. 


7. Prevent Infection from Becoming Disease


TB preventive treatment (TPT) will help prevent TB infection from becoming a more active TB disease. 


8. Discuss about TPTs


If you are at high risk of TB (e.g., close contact with someone with TB, HIV positive), then discuss TPT with your Doctor. 


9. Get BCG Vaccinated 


Countries with high TB prevalence, often vaccinate children with the Bacillus Calmette-Guérin (BCG) vaccine, which offer partial security against serious forms of TB. Discuss the advantages and risks of BCG vaccination with your Doctor, particularly if you are at high-risk area or have close contact with people with TB.   


10. Nutritious Diet and Exercise 


Lead a healthy lifestyle method with a nutritious diet and regular exercise to support your immune system. 


11. Stay Informed


Learn about TB prevention methods and get reliable information from healthcare professionals or organizations such as the World Health Organization (WHO).  


12. Check Air Quality 


Ensure that you have good ventilation in your home and workplace, as TB bacteria can be suspended in the air for extended time periods in the absence of proper ventilation. 


13. Natural Light  


Exposure to natural light could help kill TB bacteria.

 

How is TB diagnosed?


TB can be diagnosed through many methods. Here are the methods to diagnose the TB. 


Initial Assessment through Medical History

 

  • Your Doctor will enquire about your symptoms, TB  exposure, and any earlier TB tests or treatments.
    Physical Examination
  • Your Doctor will listen to the sound of your lungs and check for swollen lymph nodes.  
    TB Infection Tests 
  • TB Blood Tests like the Interferon Gamma Release Assay(IGRA) test use a blood sample to check how your immune system reacts to TB bacteria.
  • TB Skin Tests like Mantoux Tuberculin Skin Test involve a small amount of liquid being injected under the skin, and a healthcare worker will check for a reaction some 48-72 hours later.  


Other Tests

 

  • Chest X-ray test helps visualize the lungs and find any abnormalities that could denote TB symptoms.
  • Sputum Smear and Culture test involves taking a sample of coughed-up mucus (sputum) to find out the TB bacteria.  
  • The other tests are based on the suspected location of TB, and other tests such as urine or tissue samples might be required. 
  • NAAT (Nucleic Acid Amplification Test) is a molecular test that helps detect TB bacteria and drug resistance. 
  • CT Scans help get a clearer image of the lungs and other tissues if a chest X-ray doesn't offer additional information.  

 

Conclusion


There are many TB signs and symptoms. The symptoms of TB in women include a continuous persistent cough for over three weeks, coughing up blood or phlegm, weight loss, night sweats, chills, Fever, Fatigue, and Loss of appetite. TB and spinal TB are not the same, though spinal Tuberculosis (Pott's Disease) is a kind of Tuberculosis (TB) that particularly affects the spines. Skin tb symptoms include fever, weight loss, and night sweats. 


But, "TB" (tuberculosis) and "skin TB" (cutaneous tuberculosis) are not the same, however skin TB is a form of TB that is caused by the same bacteria and affects the skin. Identifying the sign and symptoms of TB through the diagnosis will help in proper treatment. TB symptoms and treatment will be properly handled by the medical team for a faster recovery.

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